Gene Machine - Venki Ramakrishnan

Gene Machine

Venki Ramakrishnan

出版社

Basic Books

出版时间

2018-11-06

ISBN

9780465093366

评分

★★★★★
书籍介绍

A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule

"Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end."

--Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. He is a senior scientist at the MRC Laboratory of Molecular Biology in Cambridge, UK, and also the president of the Royal Society in London.

用户评论
The result of doing right things at the right time. False starts and dead end are inevitable sometimes. Maybe just change the strategy and begin again. Like statistics, as long as the sample is big enough, we would get the truth mean of it anyway.
Lovely! !!
去年开会时偶遇作者签名赠书。我在飞机上看了一半回家后就放下了。对结构生物学大家争先恐后解结构的八卦听到过不少;这本书没有太多惊讶。在一个研究方法趋于成熟且高度统一的领域,到底是促进合作提倡良性竞争更重要,还是争夺资源成就个人更重要呢?
科学家现身说法自己的科研历程,比较细致用心的记录。顺祝豆瓣解封,你懂的。
作者太诚实了,很多片段很幽默,总体可读性很强,他也尝试用浅显的语言解释他的research,还是得承认很多物理的东西还是不明白
A memoir of structural biologist. 对发展史的部分有所收获,额外可以听听学科八卦。
收藏