The Biology of Cancer

Robert A. Weinberg

出版时间

2006-07-20

ISBN

9780815340782

评分

★★★★★
书籍介绍
The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology. The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature. The text is up-to-date and provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes. The Biology of Cancer provides insights into many aspects of immunology, developmental biology, and neurobiology. The exceptional full-color art program contains many images published for the first time. The book is extensively illustrated with schematic drawings, micrographs, computer-generated models and graphs. The pieces were chosen to support and clarify the concepts, as well as to supply additional interest. Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories, and for clinical professionals.
AI导读
核心看点
  • 整合三十年癌症研究,构建现代生物学概念框架
  • 通过关键实验揭示发现过程,展现逻辑推演
  • 深入解析分子与细胞层面的癌症发生机制
适合谁读
  • 生物医学专业本科生及研究生
  • 肿瘤学领域科研人员及临床医生
  • 对癌症生物学有深度兴趣的读者
读前提醒
  • 强烈建议阅读英文原版以保逻辑严密
  • 中文版翻译存在瑕疵,建议作为辅助查阅
  • 需具备基础生物学知识以理解深层机制
读者共识
  • 逻辑严密、结构清晰,堪称该领域经典
  • 作者视野宏大,兼具历史脉络与前沿假说
  • 语言通俗且富有情怀,是极佳的入门教材

本导读基于书籍简介、目录、原文摘录、短评和书评生成,不等同于全文精读。

精彩摘录
  • "最终,一个体细胞做出的细胞是否增生的决定必然反映了周围细胞的群体意见。"
  • "简单的观点是错误的,复杂的无法实现。 Paul Valery,诗人,1942年"
  • "这涉及了一个相关的问题:如果在研发过程中一种药物的真正作用只有在与其他药物联合使用时才能实现,那会怎样呢?理论上,很多抗癌药物都应该是这样的。反过来说,这就表明,在过去,很多真正有治疗效果的候选药物在单药治疗测试中失败就被遗弃;在将来,也会有许多药物是这种命运,仅仅因为它们作为多药治疗方案的组分所发挥的真正效用永远不会被测试到。这里再次强调,人们希望越来越多地了解细胞内的信号通路,从而改善这种情况。"
  • "许多肿瘤科研工作者想要了解整个生物系统,如一个活着的肿瘤细胞,而不是细胞某一组分的功能。在他们眼中,着眼于复杂系统中某一可分离组分的“还原生物学”的时代已经结束了,将这些已知组分的海量信息整合为复杂的相互作用系统,并通过生物信息学来预测这一系统的行为的新时代已经到来。"
用户评论
值得大爱的书, 从春初拖延地读到夏末, 不变地大爱, 不停地动心~流畅, 有逻辑, 有结构, 有事实, 有假说, 有历史, 有未来, 有情怀~
the canonical reading for cancer researcher
看了一点
略读过。
Classic!
想念在Emory学生物的时光…
语言通俗易懂,是很好的癌生物学入门教材
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